Volume 8, Issue 4
Winter 2009/2010

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Kinetic Expression Studies of the Hepatitis B Surface Antigen in Pichia pastoris
By Miguel Castillo et al. 

Protocol Development for Vitrification of Tissue-Engineered Cartilage
By Tanya M. Farooque, Zhenzhen Chen, Zvi Schwartz, Timothy M. Wick, Barbara D. Boyan, and Kelvin G.M. Brockbank 

Downstream Factors That Will Continue To Constrain Manufacturing Through 2013
By Eric S. Langer

FANG Vaccine: Autologous Tumor Cell Vaccine Genetically Modified to Express GM-CSF and Block Production of Furin
By Phillip Maples

Monitoring Viable Cell Density in Bioreactors Using Near-Infrared Spectroscopy
By Robert Mattes et al.

Cell Culture Bioreactor Optimization: Growing Recombinant HEK293 Cells to Produce a G-Protein-Coupled Receptor (rGPCR) Membrane Protein
By Christopher Min, Yan Jin, and Vikram Gossain

Optimized Protein Yields from Lotus Seed Utilizing CO2 Pressure Preparation and Ultrasound-Assisted Extraction
By Ya-Ju Wang, Hong-Yan Zeng, Xiao-Shan Liao, Lian-Hui Cai, and Kui Xia


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BioProcessing Journal is a peer-reviewed, quarterly publication that features the latest technological advancements and best practices for the development and production of safe and effective biologics.

Since 2002, the journal has been a leading source of industry trends and techniques for process efficiency with its content specifically designed for professionals in process and analytical methods development, manufacturing, quality systems, regulatory affairs, facility design, and contract services.

Each article is carefully selected for its content and non-commercial nature, and reviewed by one of the best known and respected Technical Advisory Boards in the industry.

BioProcessing Journal is managed by ISBioTech.