Development of Novel Transgenic Insect Cell Lines that Support Humanized Glycoprotein Production by Baculovirus Expression Vectors

by Donald L. Jarvis, PhD, Jason R. Hollister, PhD, and Jared J. Aumiller
Volume 2, Issue 1 (January/February 2003)

The baculovirus-insect cell system consists of a recombinant baculovirus vector and its host, which may be a lepidopteran insect larvae or an established lepidopteran insect cell line. Hundreds of different recombinant proteins have been produced using the baculovirus-insect cell system, facilitating biomedical research on protein structure, function, and the roles of various proteins in disease. In addition, many biotechnology companies are using this system to produce recombinant proteins for potential clinical use as vaccines, therapeutics, or diagnostic reagents...

Citation:
Jarvis DL, Hollister JR, Aumiller JJ. Development of Novel Transgenic Insect Cell Lines that Support Humanized Glycoprotein Production by Baculovirus Expression Vectors. BioProcess J, 2003; 2(1): 30-34.